Results 171 to 180 of about 8,334,111 (303)

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Tractor Testing; Belt Power Test; Caterpillar

, 1940
Text states: "1940. Checking engine R.P.M. during test no. 357." The Caterpillar D-8 is shown from the rear, where the belt pulley is located. A test engineer is measuring the belt pulley RPM with a handheld Tachometer (an RPM counter) touching the ...
Nebraska Tractor Test Laboratory
core  

Peters et al. Delusions Inventory - German version

Die deutsche Adaptation des PDI, PDI-G, als Kurz- (k = 21 Items) und Langfassung (k = 40 Items) erfasst auf drei Dimensionen (Besorgnis, Zeitliche Beschäftigung, Überzeugungsstärke) subklinischen Wahn bei Erwachsenen.
Lincoln, T. M.
core   +1 more source

DyProL: Dynamic Ensemble Representation Learning for Protein-Nucleic Acid Binding Site Prediction. [PDF]

Adv Sci (Weinh)
Li P, Liu Y, Liang L, Liu R.
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

The Revised UCLA Loneliness Scale (Russell, D., Peplau, L. A. & Cutrona, C., 1980) - Cologne version

Die KSE ist eine Adaptation des amerikanischen Originals und misst mit 20 Items Einsamkeit. Reliabilität: Die interne Konsistenz nach Cronbachs Alpha und die Split-half-Reliabilität lagen bei .88, die Stabilität nach einem 3-Monatsintervall bei rtt = .72.
Lamm, H., Stephan, E., Fäth, M.
core   +1 more source

Influence of cold plasma activation on fluoride uptake and demineralization of enamel. [PDF]

Clin Oral Investig
Schmidt A, Zingen L, Barke S, Rohland B, Harms M, Ortmann R, Viöl W, Wiegand A.   +7 more
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

A Lysis- and Sonication-Based Method for the Quantification of Extracellular Vesicle-Bound Cardiac Troponin T Using a High-Sensitivity Immunoassay. [PDF]

Biomedicines
Ding YL, Bernath-Nagy D, Heß C, Leuschner F, Katus HA, Frey N, Krohn JB, Giannitsis E.   +7 more
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source