Results 191 to 200 of about 945,073 (267)

Gender differences in infertility stress, coping and the ability to share feelings about infertility. [PDF]

Reprod Health
Szatmári A, Kovács I, Zádori J, Pataki B, Zrínyi M.   +4 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

RB loss modulates chromatin organization by regulating cohesin-dependent loops and enhancer-promoter interactions. [PDF]

Nat Commun
Lee H, Gkotinakou IM, McGrath CG, Krishnan B, Animesh S, Salinas I, Morris R, Sade-Feldman M, Haas W, Lawrence MS, Sanidas I.   +10 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Diagnostic accuracy of artificial intelligence versus 263 pediatric clinicians for childhood exanthems. [PDF]

Eur J Pediatr
Gençeli M, Metin Akcan Ö, Soran GB, Çokbiçer A, Saraç U, Üstüntaş T, Yücel M, Doğan M, Yılık Kömür E, Gençeli S, Yılmaz Dağlı H, Sarı M, Kılıç AO, Şahin S, Akkuş A.   +14 more
europepmc   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Technological, Functional, and Sensory Evaluation of Sorghum Extruded Snacks Enriched with Chokeberry Pomace. [PDF]

Foods
Janić Hajnal E, Pezo L, Banjac V, Škrobot D, Travičić V, Filipčev B, Perduh B, Kos J, Šimurina O, Cvetković B.   +9 more
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Direct RNA sequencing and signal alignment reveal RNA structure ensembles in a eukaryotic cell. [PDF]

Nat Methods
Wang J, Han J, Tan WT, Cheng AY, Aw JGA, Wang Y, Zeng G, Nagarajan N, Wan Y.   +8 more
europepmc   +1 more source