Results 71 to 80 of about 672,639 (263)

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Effect of Tanning on the Contents of Different Types of Water in Skin Collagen

open access: yesPige Kexue Yu Gongcheng
The contents of free water and bound water in inorganic Cr(Ⅲ), TWLZ and organic TWS tanned leathers were studied by centrifugal dehydration-rehydration method to explore the effect of tanning on the structure of skin collagen fibers.
Wenjun LONG   +5 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Rapid on-site Assessment of Wood Chips Moisture and Lignin for Kraft Pulping Digesters Using Portable NIR Spectroscopy

open access: yesBioResources
Rapid on-site assessment of wood quality can significantly enhance decision-making and operational efficiency in the pulp and paper industry. Spectroscopic techniques, including near-infrared (NIR) spectroscopy, can be used to characterise wood, but ...
Anka Klecina   +4 more
doaj  

Bound Water, Phase Configuration, and Dielectric Damping Effects on TDR-Measured Apparent Permittivity

open access: yesVadose Zone Journal, 2019
The time domain reflectometry (TDR) method measures the soil apparent permittivity (), which is the basis for estimation of soil volumetric water content (θ) via an empirical calibration equation or dielectric mixing model.
Miles Dyck   +3 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

The origin and impact of bound water around intrinsically disordered proteins. [PDF]

open access: yesBiophys J, 2022
Reid KM   +6 more
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

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