Results 81 to 90 of about 717,002 (287)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Bound water in Kevlar 49 fibers [PDF]

, 1981
From elemental analyses, thermogravimetric-mass spectroscopy studies and re-evaluation of previous water diffusion studies in Kevlar 49 fibers it is concluded that these fibers can contain two types of sorbed moisture. The fibers can absorb up to approx.
Morgan, R. J., Garza, R. G., Pruneda, C. O.   +2 more
core  

Tightly bound soil water introduces isotopic memory effects on mobile and extractable soil water pools

, 2017
Cryogenic vacuum extraction is the well-established method of extracting water from soil for isotopic analyses of waters moving through the soil-plant-atmosphere continuum.
Ansgar Kahmen, Matthew Pace, Prechsl, Ulrich E., Ulrich E. Prechsl, Pace, Matthew, Kahmen, Ansgar, Newberry, Sarah L., Sarah L. Newberry   +7 more
core   +1 more source

Quantitative Analysis of Bound Water Content in Marine Clay and Its Influencing Factors During the Freezing Process by Nuclear Magnetic Resonance

Journal of Marine Science and Engineering
The change in bound water content with temperature is a core issue in studying temperature effects in clayey soils. This study used nuclear magnetic resonance (NMR) techniques to measure pore water in three types of marine clay, ranging from inland to ...
Xuehan Shan, Huie Chen, Chuqiao Meng, Zuojun Lv, Qingbo Yu, Zhaoxi Wang, Qing Wang   +6 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Variations in physical, chemical and biological properties in relation to sludge dewaterability under Fe (II) – Oxone conditioning

, 2016
The mechanism of Fe (II) – oxone conditioning to improve sludge dewaterability was investigated in this study. Five different types of sludge were tested, including raw sludge (Group 1: mixed primary and secondary sludge, waste activated sludge and ...
Zhou, Yan, Xiao, Keke, Yang, Qin, Chen, Yun, Seow, Wan Yi, Zhu, Wenyu, Jiang, Xie   +6 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Bound

, 1994
Cloth waving in the wind. Heartbeat sound. Slow motion of Chinese woman practising t’ai chi. Face superimposed. Hands, body and legs wrapped by cloth superimposed. Feet stepping out of cloth. Woman on sand and rocks at sea’s edge. VO: "Through the

core  

Effect of (NH₄)₂SO₄ Solution Concentration on Bound Water Content in Ion Adsorption Rare-Earth Raw Ore

Metals
Ion adsorption rare-earth (IARE) ores, a strategic metal resource, are extracted by leaching with ammonium sulfate [(NH4)2SO4] solution, our samples have ∑REO grades of 0.032–0.079% wt%.
Yuehua Liang, Jie Wang, Zhikui Fei, Chenliang Peng, Hourui An, Zhanfeng Fan   +5 more
doaj   +1 more source