Results 151 to 160 of about 1,323,303 (307)

Systematic evaluation of the heterogeneity of topologically associating domain boundaries in a large genomic context in humans. [PDF]

NAR Genom Bioinform
Sun Y, Tommerup N, Jensen LJ, Gorodkin J.   +3 more
europepmc   +1 more source

Relations of tolerance: Syrian women, internal boundaries, and public space

Since the early days of the Syrian Civil War, the presence of Syrians in Turkey has garnered considerable attention. Together with the European Union’s efforts to externalise the perceived problem of incoming Syrians and the ...
Görentaş, Itır Aladağ, Dal, Buket Özdemir   +1 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Integrating heterogeneity into topologically associating domain boundary prediction in large genomic context in human. [PDF]

NAR Genom Bioinform
Sun Y, Jensen LJ, Tommerup N, Gorodkin J.   +3 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Chromatin accessibility classification of TAD boundaries discloses new architectural proteins. [PDF]

Nucleic Acids Res
Jácome-López K, Ledesma-Domínguez L, Esquivel-López A, Pérez-Molina R, Pénagos-Puig A, Aguilar-Lomas A, Gómora-García JC, Furlan-Magaril M.   +7 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

From parasite to bridge: redefining Cuscuta in plant communication networks. [PDF]

Mol Hortic
Eom SH, Hyun TK.
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Microstructure and Texture Evolution of GWS841 Magnesium Alloy During Hot Extrusion. [PDF]

Materials (Basel)
Yan L, He S, Su G, Feng Z, Wang N, Zheng H, Li Z.   +6 more
europepmc   +1 more source