Results 161 to 170 of about 1,323,303 (307)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Sixth Report of the Election and Boundaries Commission for the Purposes of Local Government Elections.

, 2011
Government of the Republic of Trinidad and Tobago, Election and Boundaries Commission.
core   +1 more source

Halo: a pretrained model for whole-cell segmentation from nuclei images in spatial transcriptomics. [PDF]

Brief Bioinform
Zhang X, Zhuang H, Ji Z.
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Influence of La and Ce Additions on the Microstructure and Stress Rupture Property in GH4079 Superalloy. [PDF]

Materials (Basel)
Yu P, Hou X, Liu D, Feng Y, Tian Q, Lian X.   +5 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Transcription and Three-Dimensional Genome Organization: Cause, Consequence, or Coordination? [PDF]

Bioessays
Yang D, Lei EP.
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Internal electric fields enhance reductive reactivity at MoS₂ boundaries revealed by ultrafast near-field nanospectroscopy. [PDF]

Sci Adv
Li F, Sun Q, Yang T, Sun F, Wu B, Jin S, Tian W.   +6 more
europepmc   +1 more source

'Tough choices' ahead on school boundaries

, 2009
New attendance boundaries will affect many elementary ...
Palo Alto Weekly
core