Results 41 to 50 of about 23,352 (256)
On the Numerical Solution of a Hyperbolic Inverse Boundary Value Problem in Bounded Domains
Mathematics, 2022 We consider the inverse problem of reconstructing the boundary curve of a cavity embedded in a bounded domain. The problem is formulated in two dimensions for the wave equation.
Roman Chapko, Leonidas Mindrinos
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FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
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Three-dimensional BEM for transient dynamic analysis of piezoelectric and anisotropic elastic solids
EPJ Web of Conferences, 2015 A boundary element approach based on the Green's functions in integral representation and the convolution quadrature method is presented. Proposed approach is designed for analyzing 3D initial boundary-value problems of the dynamics of general ...
Igumnov Leonid +4 more
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Application of Collocation BEM for Axisymmetric Transmission Problems in Electro- and Magnetostatics
Mathematical Modelling and Analysis, 2016 This paper considers the numerical solution of boundary integral equations for an exterior transmission problem in a three-dimensional axisymmetric domain.
Olga Lavrova, Viktor Polevikov
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Method for solving plane unsteady contact problems for rigid stamp and elastic half-space with a cavity of arbitrary geometry and location [PDF]
INCAS Bulletin, 2020 In the work, the process of unsteady contact interaction of rigid stamp and elastic half-space having a recessed cavity of arbitrary geometry and location with a smooth boundary was investigated.
Yulong LI +3 more
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
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Kurdistan Journal of Applied Research, 2017 A Robin problem is a mixed problem with a linear combination of Dirichlet and Neumann D-N conditions. The aim of this paper are presents a new boundary integral equation BIE method for the solution of unbounded Robin boundary value problem BVP in the ...
Shwan H. H. Al-Shatri +2 more
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
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