Results 81 to 90 of about 23,352 (256)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

On a method for constructing the Green function of the Dirichlet problem for the Laplace equation

open access: yesҚарағанды университетінің хабаршысы. Математика сериясы
The study of boundary value problems for elliptic equations is of both theoretical and applied interest. A thorough study of model physical and spectral problems requires an explicit and effective representation of the problem solution.
Т.Ш. Кaльменов
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Integral Equation Analysis of EM Scattering from Multilayered Metallic Photonic Crystal Accelerated with Adaptive Cross Approximation

open access: yesInternational Journal of Antennas and Propagation, 2015
A space-domain integral equation method accelerated with adaptive cross approximation (ACA) is presented for the fast and accurate analysis of electromagnetic (EM) scattering from multilayered metallic photonic crystal (MPC).
Jianxun Su   +4 more
doaj   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

open access: yesFEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

An Approximate Grid Solution of a Nonlocal Boundary Value Problem with Integral Boundary Condition for Laplace's Equation

open access: yesITM Web of Conferences, 2018
A new method for the solution of a nonlocal boundary value problem with integral boundary condition for Laplace's equation on a rectangular domain is proposed and justified.
Dosiyev Adıgüzel A., Reis Rifat
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

On explicit and numerical solvability of parabolic initial-boundary value problems

open access: yesBoundary Value Problems, 2006
A homogeneous boundary condition is constructed for the parabolic equation (∂t+I−Δ)u=f in an arbitrary cylindrical domain Ω×ℝ (Ω⊂ℝn being a bounded domain, I and Δ being the identity operator and the Laplacian ...
Olga Lepsky, Alexander Kozhevnikov
doaj   +1 more source

Boundary integral based polygon wall representation in the MPS method

open access: yesNihon Kikai Gakkai ronbunshu, 2018
The particle methods are suited to simulate fluid flow problems with large boundary deformation. The moving particle semi-implicit (MPS) method is one of the representative particle methods for incompressible flow.
Takuya MATSUNAGA   +2 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

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