Results 41 to 50 of about 647,771 (267)
During November-December of 2022, the climate of Beijing-Tianjin-Hebei (BTH) showed significant cold and warm transition, and the average air temperature difference between November and December was 10.6 °C, ranked first with 1971 and 1980 since 1961 ...
Xuxu GAO, Shaojing CHE, Haoyu DU
doaj +1 more source
Boundary Value Problems with Compatible Boundary Conditions [PDF]
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Karakostas, G. L., Palamides, P. K.
openaire +2 more sources
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Accurately extracting long-term urban and rural settlement (URS) information is crucial for studying urbanization processes and their impacts on the ecological environment.
Xiaopeng Li +5 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
North China experienced an extreme precipitation event from July 29 to August 1, 2023 (i.e., the “23.7” event) causing severe floods, significant infrastructure damage and multiple fatalities.
Xiaofan Li +6 more
doaj +1 more source
Game without game: to Gilles Deleuze’s game concept
The article provides a critical analysis of the "ideal game" concept by Gilles Deleuze. The problematic type of Deleuze's judgments about the game leads to the fact that the game is understood by him as a logical subject devoid of the predicate.
Yuriy A. Razinov, Dmitriy A. Kechaev
doaj +1 more source
Boundary conditions in supergravity on a manifold with boundary [PDF]
We explain why it is necessary to use boundary conditions in the proof of supersymmetry of a supergravity action on a manifold with boundary. Working in both boundary (``downstairs'') and orbifold (``upstairs'') pictures, we present a bulk-plus-boundary/brane action for the five-dimensional (on-shell) supergravity which is supersymmetric with the use ...
openaire +4 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source

