Results 121 to 130 of about 1,888,468 (273)

A large-scale flume model test system with controllable/measurable hydraulic and gas boundary conditions

Yantu gongcheng xuebao
The accurate evaluation of water-gas transport is important for pollution control in landfill earthen covers. With poor sealing effects, most of the existing model test instruments cannot accurately control the air pressure and simulate the boundary ...
LU Zichen 1, 2, CHEN Rui 1, 2, WANG Hao 1, 2, CHEN Zibin 1, 2, GUO Haowen 3, HUANG Junwen 1, 2
doaj   +1 more source

LiDAR Point Cloud Data Combined Structural Analysis Based on Strong Form Meshless Method Using Essential Boundary Condition Capturing. [PDF]

Sensors (Basel), 2023
Seo KW, Yoon YC, Lee SH.
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Parametric analysis of an efficient boundary condition to control outlet flow rates in large arterial networks. [PDF]

Sci Rep, 2022
Lo SCY, McCullough JWS, Coveney PV.
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Coexisting steady-state solutions of a class of reaction-diffusion systems with different boundary conditions

Electronic Journal of Qualitative Theory of Differential Equations
In this work, we investigate a class of reaction-diffusion system in which both species are influenced by self-diffusion. By introducing two particular functions, we provide a complete characterization of the parameter ranges such that coexisting steady ...
Ningning Zhu, Dongpo Hu, Huili Bi
doaj   +1 more source

Effective data sampling strategies and boundary condition constraints of physics-informed neural networks for identifying material properties in solid mechanics. [PDF]

Appl Math Mech, 2023
Wu W, Daneker M, Jolley MA, Turner KT, Lu L.   +4 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Simulation of the conditions for the flow of fresh lubricant in the inter-pad groove of a fluid film thrust bearing

Учёные записки Казанского университета: Серия Физико-математические науки
This article describes different modeling options for mixing the hot lubricant of the upstream pad of a fluid film bearing and the fresh lubricant of the oil-feeding inter-pad groove.
N. V. Sokolov, P. E. Fedotov
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source