Results 51 to 60 of about 230,269 (263)

An Unfitted Method with Elastic Bed Boundary Conditions for the Analysis of Heterogeneous Arterial Sections

open access: yesMathematics, 2023
This manuscript presents a novel formulation for a linear elastic model of a heterogeneous arterial section undergoing uniform pressure in a quasi-static regime. The novelties are twofold.
Stephan Gahima   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Continuity of the free boundary in elliptic problems with Neuman boundary condition

open access: yesElectronic Journal of Differential Equations, 2015
We show the continuity of the free boundary in a class of two dimensional free boundary problems with Neuman boundary condition, which includes the aluminium electrolysis problem and the heterogeneous dam problem with leaky boundary condition.
Abderachid Saadi
doaj  

Neumann boundary condition for Abelian BPS vortices

open access: yesJournal of High Energy Physics, 2023
We study abelian BPS vortices on a surface S with boundary, which satisfy the Neumann boundary condition on the norm of the scalar field, or equivalently, that the current along the boundary vanishes.
N. S. Manton, Boan Zhao
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Numerical Experiment for Ultrasonic-Measurement-Integrated Simulation of Developed Laminar Pipe Flow Using Axisymmetric Model

open access: yesJournal of Biomechanical Science and Engineering, 2008
Many studies have been carried out on the relationship between the occurrence and progression of circulatory diseases and hemodynamics. However, it is difficult to obtain accurate and detailed information on blood flow in the living body with existing ...
Lei LIU   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Boundary condition of polyelectrolyte adsorption [PDF]

open access: yesPhysical Review E, 2006
The modification of the boundary condition for polyelectrolyte adsorption on charged surface with short-ranged interaction is investigated under two regimes. For weakly charged Gaussian polymer in which the short-ranged attraction dominates, the boundary condition is the same as that of the neutral polymer adsorption.
openaire   +3 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Wave interaction with caisson breakwater considering large sliding movements in mesh-free Lagrangian coordinate

open access: yesنشریه مهندسی دریا, 2019
An important point in design of coastal structures is their structural response to design waves. In this study, wave interaction with a caisson breakwater is studied numerically by means of a modified SPH method. An efficient method is introduced to take
Amir Taherkhani, Hassan Akbari
doaj  

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