Results 71 to 80 of about 230,269 (263)
Navier-Stokes equation with slip-like boundary condition
Electronic Journal of Differential Equations, 2009 The aim of this note is to investigate a time-discretized 2-dimensional Navier-Stokes equation with a slip-like boundary condition, which arises in the melting ice problem. We prove the existence and uniqueness of a weak solution.
Ken'ichi Hashizume +2 more
doaj
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Boundary value problems with an integral constraint
Electronic Journal of Differential Equations, 2015 We show the existence of solutions for a second-order ordinary differential equation coupled with a boundary-value condition and an integral condition.
Elisabetta M. Mangino, Eduardo Pascali
doaj
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Generalized solution of boundary value problem with an inhomogeneous boundary condition
MANAS: Journal of Engineering, 2019 In this problem, we study the solution to boundary value problem for a controlled oscillation process, described by Fredholm integro-differential equation with an inhomogeneous boundary condition.
Elmira Abdyldaeva +2 more
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
FEBS Letters, EarlyView.Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Fine-Grained Boundary Conditions in Field-Based Routing
SensorsIn the realm of industrial wireless mesh networks, an efficient routing protocol is highly demanded to play a crucial role in ensuring that packets are efficiently directed along shorter and congestion-free routes toward gateways. Field-based routing has
Jihoon Sung, Yeunwoong Kyung
doaj +1 more source