Results 81 to 90 of about 295,105 (311)

On the adjoint of a symmetric operator [PDF]

, 2007
In general it is a non-trivial task to determine the adjoint S* of an unbounded symmetric operator S in a Hilbert or Krein space. We propose a method to specify S* explicitly which makes use of two boundary mappings that satisfy an abstract Green's ...
Meda S., Nelly Villamizar, CATALISANO, MARIA VIRGINIA, E. CARLINI, Matilde Lalín, Saito, Morihiko, Mauceri G., Fernandes de Oliveira, GM, Yuzvinsky, Sergey, Nero Budur, Vallarino, Maria, PICCIONE, P., Matthias Langer, Behrndt, Jussi, Frank Sottile (7161257), Morihiko Saito, Hynek Kovařík, PEREIRA, Antonio L., M. V. CATALISANO, Budur, Nero, Langer, Matthias, Elisa Postinghel, Stefano Meda, Lotoreichik, Vladimir, JAVALOYES, M. A., Catalisano M.V, Carlini, Enrico, Mauceri, G., Giancarlo Mauceri, Sergey Yuzvinsky, CATALISANO M. V., PEREIRA, Marcone C., Jussi Behrndt, MAUCERI, GIANCARLO, Wadim Zudilin, Veys, Willem, S. Meda, Detchat Samart, M. Vallarino, Catalisano, M.V., G. Mauceri, Frank Sottile, Elisa Postinghel (2887796), BILIOTTI, L., Meda, S., Kovarik, Hynek, Maria Vallarino, Nelly Villamizar (7161260)   +47 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Wave interaction with caisson breakwater considering large sliding movements in mesh-free Lagrangian coordinate

نشریه مهندسی دریا, 2019
An important point in design of coastal structures is their structural response to design waves. In this study, wave interaction with a caisson breakwater is studied numerically by means of a modified SPH method. An efficient method is introduced to take
Amir Taherkhani, Hassan Akbari
doaj  

Boundary condition of polyelectrolyte adsorption [PDF]

Physical Review E, 2006
The modification of the boundary condition for polyelectrolyte adsorption on charged surface with short-ranged interaction is investigated under two regimes. For weakly charged Gaussian polymer in which the short-ranged attraction dominates, the boundary condition is the same as that of the neutral polymer adsorption.
openaire   +3 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Implementation of boundary conditions for optimized high-order compact schemes [PDF]

, 1997
The optimized high-order compact (OHOC) finite difference schemes, proposed as central schemes are used for aeroacoustic computations on interior nodes.
Kim, J.W., Lee, D.J.
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Integral representation of a solution to the Stokes-Darcy problem [PDF]

, 2015
With methods of potential theory we develop a representation of a solution of the coupled Stokes-Darcy model in a Lipschitz domain for boundary data in H-1 ...
Medková, Dagmar, Ptashnyk, Mariya, Ptashnyk, Mariya; id_orcid, Werner Varnhorn, Dagmar Medková, Varnhorn, Werner, Mariya Ptashnyk   +6 more
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source