Results 101 to 110 of about 648,510 (309)

Mathematical analysis of parallel convective exchangers with general lateral boundary conditions using generalized graetz modes [PDF]

open access: yes, 2013
We propose a mathematical analysis of parallel convective exchangers for any general but longitudinally invariant domains. We analyze general Dirichlet or Neumann prescribed boundary conditions at the outer solid domain.
Plouraboué, Franck   +2 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Non-reflecting boundary conditions and tensile instability in smooth particle hydrodynamics [PDF]

open access: yes, 2012
This thesis aimed at the understanding and further development of smoothed particle hydrodynamics (SPH). The first part described the implementations of non-reflecting boundary conditions for elastic- waves in SPH. The second part contains a stability
Powell, Seimon
core  

Nonlinear control of unsteady finite-amplitude perturbations in the Blasius boundary-layer flow [PDF]

open access: yes, 2013
The present work provides an optimal control strategy, based on the nonlinear Navier–Stokes equations, aimed at hampering the rapid growth of unsteady finite-amplitude perturbations in a Blasius boundary-layer flow.
DE PALMA, Pietro   +2 more
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Positive solutions to a third order nonlocal boundary value problem with a parameter [PDF]

open access: yesOpuscula Mathematica
We present some sufficient conditions for the existence of positive solutions to a third order differential equation subject to nonlocal boundary conditions.
Gabriela Szajnowska, Mirosława Zima
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Investigation of matrix nullity for the second order discrete nonlocal boundary value problem

open access: yesLietuvos Matematikos Rinkinys, 2013
In this paper we investigate the relation between the matrix nullity of the second order discrete boundary value problem and nonlocal boundary conditions. The obtained classification and examples are also presented.
Gailė Paukštaitė, Artūras Štikonas
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

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