Results 81 to 90 of about 8,811,113 (297)
On singular $p$-Laplacian boundary value problems involving integral boundary conditions
We prove the existence of positive solutions for the $p$-Laplacian equations \[-(\phi (u^{\prime }))^{\prime }=\lambda f(t,u),\qquad t\in (0,1) \] with integral boundary conditions. Here $\lambda $ is a positive parameter, $\phi (s)=|s|^{p-2}s,p>1,\ f:(0,
Dang Dinh Hai, Xiao Wang
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Fluid boundary conditions from AdS/BCFT
In this paper, we initiate our program to classify conformal fluid boundary conditions, by utilizing the fluid/gravity correspondence in the AdS/BCFT correspondence.
Tomohito Shiga, Kenta Suzuki
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Nonlinear Schrodinger equations on the half-line with nonlinear boundary conditions
In this article, we study the initial boundary value problem for nonlinear Schrodinger equations on the half-line with nonlinear boundary conditions $$ u_x(0,t)+\lambda|u(0,t)|^ru(0,t)=0,\quad \lambda\in\mathbb{R}-\{0\},\; r> 0.
Ahmet Batal, Turker Ozsari
doaj
We establish the existence of positive solutions to a class of a singular nonlinear Hadamard-type fractional differential equations with infinite-point boundary conditions (BCs) or integral BCs.
A. M. A. El-Sayed, F. M. Gaafar
doaj +1 more source
Modifications to a turbulent inflow generation method for boundary-layer flows [PDF]
NUMERICAL simulations of turbulent boundary layers require inflow/outflow boundary conditions. Downstream flow is particularly sensitive to the inlet boundary condition; it is necessary to provide a realistic, coherent series of time-varying velocity ...
Chung, Yongmann M. +9 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
A varifold formulation of mean curvature flow with Dirichlet or dynamic boundary conditions [PDF]
We consider the sharp interface limit of the Allen-Cahn equation with Dirichlet or dynamic boundary conditions and give a varifold characterization of its limit which is formally a mean curvature flow with Dirichlet or dynamic boundary conditions.
Takasao, Keisuke +4 more
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source

