Results 61 to 70 of about 8,811,113 (297)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Fractional-order boundary value problem with Sturm-Liouville boundary conditions

open access: yesElectronic Journal of Differential Equations, 2015
Using the new conformable fractional derivative, which differs from the Riemann-Liouville and Caputo fractional derivatives, we reformulate the second-order conjugate boundary value problem in this new setting.
Douglas R. Anderson, Richard I. Avery
doaj  

Linear ODE with nonlocal boundary conditions and Green’s functions for such problems

open access: yesLietuvos Matematikos Rinkinys, 2019
In this article we investigate a formula for the Green’s function for the n-order linear differential equation with n additional conditions. We use this formula for calculating the Green’s function for problems with nonlocal boundary conditions.
Svetlana Roman, Artūras Štikonas
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Nonlocal problems for hyperbolic equations from the viewpoint of strongly regular boundary conditions

open access: yesElectronic Journal of Differential Equations, 2020
In this article, we consider a nonlocal problem for hyperbolic equation with integral conditions and show their close connection with the notion of strongly regular boundary conditions.
Ludmila S. Pulkina
doaj  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Quantum detection of boundary conditions

open access: yesPhysics Letters B
The quantum detection of spacetime conicity was investigated in reference Cong et al. (2021) [9] through the analysis of the response function of an Unruh-deWitt detector coupled to a massless scalar field.
Jefferson Monção da Silva   +1 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Magnetohydrodynamic channel flow and variational principles

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1987
This paper deals with magnetohydrodynamic channel flow problems. Attention is given to a variational principle where the boundary conditions are incorporated via a suitable functional which is stationary at the solution of the given problem; the trial ...
Adnan A. El-Hajj
doaj   +1 more source

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