Results 61 to 70 of about 648,510 (309)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
MathematicsSeismic wave propagation in complex terrains, especially in the presence of air layers, plays a crucial role in accurate subsurface imaging. However, the influence of different boundary conditions on seismic wave propagation characteristics has not been ...
Ying Zhang +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Existence of solutions to Sturm–Liouville boundary value problems
Electronic Journal of Qualitative Theory of Differential EquationsWe study the solvability of Sturm–Liouville boundary value problems for $x''=f(t,x,x'), t\in(0,1)$. The nonlinearity can be defined on a bounded set and is required to be continuous on its subset.
Gabriela Mihaylova, Petio Kelevedjiev
doaj +1 more source
Boundary conditions for quadrupolar metamaterials
New Journal of Physics, 2014 One of the long-standing problems in effective medium theories is using the knowledge of the bulk material response to predict the behavior of the electromagnetic fields at the material boundaries.
Mário G Silveirinha
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Computing continuous-time growth models with boundary conditions via wavelets [PDF]
, 2004 This paper presents an algorithm for approximating the solution of deterministic/stochastic continuous-time growth models based on the Euler's equation and the transversality conditions.
Mercedes Esteban-bravo +3 more
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Fractional-order boundary value problem with Sturm-Liouville boundary conditions
Electronic Journal of Differential Equations, 2015 Using the new conformable fractional derivative, which differs from the Riemann-Liouville and Caputo fractional derivatives, we reformulate the second-order conjugate boundary value problem in this new setting.
Douglas R. Anderson, Richard I. Avery
doaj
Linear ODE with nonlocal boundary conditions and Green’s functions for such problems
Lietuvos Matematikos Rinkinys, 2019 In this article we investigate a formula for the Green’s function for the n-order linear differential equation with n additional conditions. We use this formula for calculating the Green’s function for problems with nonlocal boundary conditions.
Svetlana Roman, Artūras Štikonas
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The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source