Results 151 to 160 of about 404,554 (315)

Optimal Control of an Allen-Cahn Equation with Singular Potentials and Dynamic Boundary Condition

, 2015
In this paper, we investigate optimal control problems for Allen-Cahn equations with singular nonlinearities and a dynamic boundary condition involving singular nonlinearities and the Laplace-Beltrami operator.
COLLI, PIERLUIGI, Sprekels, Jürgen, Jürgen Sprekels   +2 more
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Analysis of boundary effects in iterative learning control

, 2013
Boundary effects in iterative learning control (ILC) algorithms are considered in this article. ILC algorithms involve filtering of input and error signals over finite-time intervals, often using non-causal filters, and it is important that the boundary ...
Wallén, Johanna,, Gunnarsson, Svante, Norrlöf, Mikael,, Norrlöf, Mikael, Gunnarsson, Svante,, Wallén, Johanna   +5 more
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

VALUATION OF BOUNDARY-LINKED ASSETS [PDF]

This article studies the valuation of boundary-linked assets and their derivatives in continuous-time markets. Valuing boundary-linked assets requires the solution of a stochastic differential equation with boundary conditions, which, often, is not ...
Mercedes Esteban-Bravo, Jose M. Vidal-Sanz   +1 more
core  

Inverse Optimality of Regulation Design for Korteweg-De Vries-Burgers Equation

IEEE Access
In optimal control, it is often necessary to solve Hamilton-Jacobi-Isaacs (HJI) partial differential equation, but it is not only difficult to solve, sometimes even impossible to solve.
Xiushan Cai, Cong Lin
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Growth, Structure and Prediction of the Thermal Internal Boundary Layer

, 1988
The Thermal internal Boundary Layer (TIBL) is a dynamic and turbulent mesoscale feature of the coastal atmosphere that forms over the land during conditions of onshore flow.
Comrie, Andrew Charles
core  

Approximate robust output regulation of boundary control systems

, 2018
We extend the internal model principle for systems with boundary control and boundary observation, and construct a robust controller for this class of systems.
Humaloja, Jukka-Pekka, Humaloja, Jukka Pekka, Paunonen, Lassi, Kurula, Mikael   +3 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source