Results 111 to 120 of about 23,409 (291)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Shielding properties of a conducting bar calculated with a boundary integral method [PDF]

open access: yesAdvances in Radio Science, 2005
A plane rectangular bar of conducting and permeable material is placed in an external low-frequency magnetic field. The shielding properties of this object are investigated by solving the given plane eddy current problem for the vector potential with the
L. O. Fichte   +3 more
doaj  

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

A coupled point particle two-phase heat and mass transfer model for dispersed flows based on Boundary Element Methods

open access: yes
In dispersed multiphase flow processes we encounter coupled heat, mass and momentum transfer between the disoersed and the continuous phase. In the context of the subdomain Boundary Domain Integral Method (BDIM) solution of the Navier-Stokes equations a ...
Gomboc, Timi   +3 more
core   +2 more sources

Exact solution and its pertinent numerical methodology for wave equation subject to local boundary or nonlocal integral conditions

open access: yesBoundary Value Problems
In this paper, we propose exact solution as well as an efficacious numerical method for the wave equation subject to local boundary or nonlocal integral conservation conditions.
Yao-Hsin Hwang, Pi-Yen Lin
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

The problem with the missing Goursat condition at the boundary of the domain for a degenerate hyperbolic equation with a singular coefficient

open access: yesҚарағанды университетінің хабаршысы. Математика сериясы
The work is devoted to the formulation and study of the solvability for a problem with missing conditions on the characteristic boundary of the domain and an analogue of the Frankl condition on the segment of the degeneracy for a hyperbolic equation ...
М. Мирсабуров   +3 more
doaj   +1 more source

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