Results 41 to 50 of about 1,402,818 (287)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul   +13 more
wiley   +1 more source

Inverse estimates for elliptic boundary integral operators and their application to the adaptive coupling of FEM and BEM [PDF]

open access: yes, 2012
We prove inverse-type estimates for the four classical boundary integral operators associated with the Laplace operator. These estimates are used to show convergence of an h-adaptive algorithm for the coupling of a finite element method with a boundary ...
Aurada, Markus   +5 more
core  

Dietary Protein Intake and Peritoneal Protein Losses in Peritoneal Dialysis Patients

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) patients lose protein in their waste dialysate, potentially increasing their risk for malnutrition. We wished to determine whether there was any association between losses and dietary protein intake (DPI). Methods DPI was assessed from 24‐h dietary recall using Nutrics software.
Haalah Shaaker, Andrew Davenport
wiley   +1 more source

Cis-regulatory modes of Ultrabithorax inactivation in butterfly forewings

open access: yeseLife
Hox gene clusters encode transcription factors that drive regional specialization during animal development: for example the Hox factor Ubx is expressed in the insect metathoracic (T3) wing appendages and differentiates them from T2 mesothoracic ...
Amruta Tendolkar   +6 more
doaj   +1 more source

Adaptive boundary element methods with convergence rates [PDF]

open access: yes, 2011
This paper presents adaptive boundary element methods for positive, negative, as well as zero order operator equations, together with proofs that they converge at certain rates.
Gantumur, Tsogtgerel
core  

Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai   +4 more
wiley   +1 more source

A Typology of Stranded Phonologically Weak Elements

open access: yesStudies in Polish Linguistics, 2023
The paper presents a unified account of a number of superficially very different cases from Japanese, Serbo-Croatian, German, and Dutch where a phonologically weak element is stranded without a host.
Željko Bošković
doaj   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

SYNTHESIS OF BOUNDARY CONDITIONS IDENTIFICATION METHOD AND FINITE ELEMENT METHOD. RECTANGULAR PLATES

open access: yesАвіаційно-космічна техніка та технологія, 2017
The key problem in the use of previously proposed boundary conditions identification method is the solution of intermediate boundary-value problems.
Сиявуш Ахмедович Халилов   +3 more
doaj   +1 more source

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