Results 71 to 80 of about 1,397,215 (290)
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Composite micromechanical modeling using the boundary element method [PDF]
The use of the boundary element method for analyzing composite micromechanical behavior is demonstrated. Stress-strain, heat conduction, and thermal expansion analyses are conducted using the boundary element computer code BEST-CMS, and the results ...
Goldberg, Robert K., Hopkins, Dale A.
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Probabilistic boundary element method [PDF]
The purpose of the Probabilistic Structural Analysis Method (PSAM) project is to develop structural analysis capabilities for the design analysis of advanced space propulsion system hardware.
Cruse, T. A., Raveendra, S. T.
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
COMGEN-BEM: Boundary element model generation for composite materials micromechanical analysis [PDF]
Composite Model Generation-Boundary Element Method (COMGEN-BEM) is a program developed in PATRAN command language (PCL) which generates boundary element models of continuous fiber composites at the micromechanical (constituent) scale.
Goldberg, Robert K.
core +1 more source
FEATS - Finite element thermal stress analysis of plane or axisymmetric solids [PDF]
, 1971 FEATS computer code uses finite element analysis to calculate steady state temperature and thermal stress fields for either axisymmetric or plane two-dimensional bodies with boundary conditions, including specified displacements, loads, and thermal ...
Swanson, J. A.
core +1 more source
Finite element approximation of source term identification with TV-regularization
, 2019 In this paper we investigate the problem of recovering the source term in an elliptic system from a measurement of the state on a part of the boundary.
Hinze, Michael, Quyen, Tran Nhan Tam
core +1 more source