Results 81 to 90 of about 1,137,944 (246)

Prediction of waterjet excited underwater radiated noise by boundary element method

open access: yesZhongguo Jianchuan Yanjiu, 2017
Aiming to mitigate impact of the uncertain boundary conditions setting on the underwater radiated noise calculation, the numerical prediction method of calculating the underwater radiated noise of a waterjet by the one-step boundary element method was ...
LIU Qiang   +4 more
doaj   +1 more source

Boundary Integral Equations for the Laplace-Beltrami Operator

open access: yes, 2008
We present a boundary integral method, and an accompanying boundary element discretization, for solving boundary-value problems for the Laplace-Beltrami operator on the surface of the unit sphere $\S$ in $\mathbb{R}^3$.
D. Crowdy   +6 more
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

A reduced-order boundary element method for two-dimensional acoustic scattering

open access: yesFrontiers in Physics
This study presents a novel method for wideband acoustic analysis using the Boundary Element Method (BEM), addressing significant computational challenges. Traditional BEM requires repetitive computations across different frequencies due to the frequency-
Senhao Zhong   +4 more
doaj   +1 more source

Applications of FEM and BEM in two-dimensional fracture mechanics problems [PDF]

open access: yes
A comparison of the finite element method (FEM) and boundary element method (BEM) for the solution of two-dimensional plane strain problems in fracture mechanics is presented in this paper.
Min, J. B.   +2 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

A Hybrid Boundary Element Method for Elliptic Problems with Singularities

open access: yes, 2010
The singularities that arise in elliptic boundary value problems are treated locally by a singular function boundary integral method. This method extracts the leading singular coefficients from a series expansion that describes the local behavior of the ...
Boudouvis, Andreas G.   +2 more
core  

A Comparison Study of Two Methods for Elliptic Boundary Value Problems [PDF]

open access: yes, 2013
In this paper, we perform a comparison study of two methods (the embedded boundary method and several versions of the mixed finite element method) to solve an elliptic boundary value ...
Du, Jian   +3 more
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

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