Results 81 to 90 of about 1,137,021 (285)
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
A reduced-order boundary element method for two-dimensional acoustic scattering
Frontiers in PhysicsThis study presents a novel method for wideband acoustic analysis using the Boundary Element Method (BEM), addressing significant computational challenges. Traditional BEM requires repetitive computations across different frequencies due to the frequency-
Senhao Zhong +4 more
doaj +1 more source
COMGEN-BEM: Boundary element model generation for composite materials micromechanical analysis [PDF]
Composite Model Generation-Boundary Element Method (COMGEN-BEM) is a program developed in PATRAN command language (PCL) which generates boundary element models of continuous fiber composites at the micromechanical (constituent) scale.
Goldberg, Robert K.
core +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Applications of FEM and BEM in two-dimensional fracture mechanics problems [PDF]
A comparison of the finite element method (FEM) and boundary element method (BEM) for the solution of two-dimensional plane strain problems in fracture mechanics is presented in this paper.
Min, J. B. +2 more
core +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
A method for magnetocardiography functional localization based on boundary element method and Nelder-Mead simplex algorithm. [PDF]
Ann Noninvasive Electrocardiol, 2021 Lu Z, Jiang D, Yang J.
europepmc +1 more source
A Hybrid Boundary Element Method for Elliptic Problems with Singularities
, 2010 The singularities that arise in elliptic boundary value problems are treated locally by a singular function boundary integral method. This method extracts the leading singular coefficients from a series expansion that describes the local behavior of the ...
Boudouvis, Andreas G. +2 more
core
A simple approach to the numerical simulation with trimmed CAD surfaces
, 2015 In this work a novel method for the analysis with trimmed CAD surfaces is presented. The method involves an additional mapping step and the attraction stems from its sim- plicity and ease of implementation into existing Finite Element (FEM) or Boundary ...
Beer, Gernot +2 more
core +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source