Results 71 to 80 of about 228,192 (267)
On selecting the critical boundary functions in group-sequential trials with two time-to-event outcomes. [PDF]
Contemp Clin Trials, 2021 Hamasaki T +3 more
europepmc +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Review of the no-boundary wave function
Physics Reports, 2023 When the universe is treated as a quantum system, it is described by a wave function. This wave function is a function not only of the matter fields, but also of spacetime. The no-boundary proposal is the idea that the wave function should be calculated by summing over geometries that have no boundary to the past, and over regular matter configurations
openaire +4 more sources
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Computer Assisted Methods in Engineering and Science, 2023 The purpose of the paper is to propose of a way of constructing trial functions for the indirect Trefftz method as applied to harmonic problems possessing circular holes, circular inclusions, corners, slits, and symmetry.
Jan A. Kołodziej, Anita Uściłowska
doaj
Boundary values of analytic functions [PDF]
Communications in Mathematical Physics, 1968 It is known that a complex — valued continuous functionS(x) as well as a Schwartz distribution on the real axis can be extended in the complex plane minus the support ofS to an analytic functionŜ(z). In the case of a continuous function the jump ofŜ(z) on the real axis represents exactlyS(x): $$\mathop {\lim }\limits_{\varepsilon \to 0 + } [\hat S(x
openaire +2 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
The S-matrix and boundary correlators in flat space
Journal of High Energy PhysicsWe consider the path integral of a quantum field theory in Minkowski spacetime with fixed boundary values (for the elementary fields) on asymptotic boundaries.
Diksha Jain +5 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source