Results 91 to 100 of about 3,865,749 (296)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
The purpose of the paper is to propose of a way of constructing trial functions for the indirect Trefftz method as applied to harmonic problems possessing circular holes, circular inclusions, corners, slits, and symmetry.
Jan A. Kołodziej, Anita Uściłowska
doaj
In this paper, generalized Green’s functions for second-order discrete boundaryvalue problems with nonlocal boundary conditions are investigated, where the necessary and sufficient existence condition of discrete Green’s function is not satisfied and ...
Gailė Paukštaitė, Artūras Štikonas
doaj +1 more source
On computing boundary functional sums
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Observation of the quality of the waters along the United States an Mexico border
No ...
International Boundary and Water Commission
core
The S-matrix and boundary correlators in flat space
We consider the path integral of a quantum field theory in Minkowski spacetime with fixed boundary values (for the elementary fields) on asymptotic boundaries.
Diksha Jain +5 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source

