Results 101 to 110 of about 268,935 (316)
On Boundary Conditions Parametrized by Analytic Functions
Computer algebra can answer various questions about partial differential equations using symbolic algorithms. However, the inclusion of data into equations is rare in computer algebra. Therefore, recently, computer algebra models have been combined with Gaussian processes, a regression model in machine learning, to describe the behavior of certain ...
Markus Lange-Hegermann, Daniel Robertz
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The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Two-point boundary correlation functions of dense loop models
We investigate six types of two-point boundary correlation functions in the dense loop model. These are defined as ratios $Z/Z^0$ of partition functions on the $m\times n$ square lattice, with the boundary condition for $Z$ depending on two points $x$
Alexi Morin-Duchesne, Jesper Lykke Jacobsen
doaj +1 more source
Boundary values of analytic functions [PDF]
It is known that a complex — valued continuous functionS(x) as well as a Schwartz distribution on the real axis can be extended in the complex plane minus the support ofS to an analytic functionŜ(z). In the case of a continuous function the jump ofŜ(z) on the real axis represents exactlyS(x): $$\mathop {\lim }\limits_{\varepsilon \to 0 + } [\hat S(x
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An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
On selecting the critical boundary functions in group-sequential trials with two time-to-event outcomes. [PDF]
Hamasaki T +3 more
europepmc +1 more source
The lithosphere-asthenosphere boundary in the North-West Atlantic region [PDF]
A detailed knowledge of the thickness of the lithosphere in the north Atlantic is an important parameter for understanding plate tectonics in that region.
Schweitzer, J. +16 more
core +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Review of the no-boundary wave function
When the universe is treated as a quantum system, it is described by a wave function. This wave function is a function not only of the matter fields, but also of spacetime. The no-boundary proposal is the idea that the wave function should be calculated by summing over geometries that have no boundary to the past, and over regular matter configurations
openaire +4 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source

