Results 41 to 50 of about 593,564 (351)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Boundary value problems for essentially-loaded parabolic equation
Қарағанды университетінің хабаршысы. Математика сериясы, 2018 In this paper we investigate the first boundary value problem for essentially loaded equation of heat conduction, i.e. when laden terms are derivatives for any finite order.
M.I. Ramazanov +4 more
doaj +1 more source
A Numerical Study for the Dirichlet Problem of the Helmholtz Equation
Mathematics, 2021 In this paper, an effective numerical method for the Dirichlet problem connected with the Helmholtz equation is proposed. We choose a single-layer potential approach to obtain the boundary integral equation with the density function, and then we deal ...
Yao Sun, Shijie Hao
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Three new approaches for solving a class of strongly nonlinear two-point boundary value problems
Boundary Value Problems, 2021 Three new and applicable approaches based on quasi-linearization technique, wavelet-homotopy analysis method, spectral methods, and converting two-point boundary value problem to Fredholm–Urysohn integral equation are proposed for solving a special case ...
Monireh Nosrati Sahlan, Hojjat Afshari
doaj +1 more source
Boundary Integral Solutions of the Heat Equation [PDF]
Mathematics of Computation, 1986 The Boundary Integral Method (BIM) has recently become quite popular because of its ability to provide cheap numerical solutions to the Laplace equation. This paper describes an attempt to apply a similar approach to the (time-dependent) heat equation in two space variables.
openaire +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Localized boundary-domain integral formulations for problems with variable coefficients
, 2002 Specially constructed localized parametrixes are used in this paper instead of a fundamental solution to reduce a boundary value problem with variable coefficients to a localized boundary-domain integral or integro-differential equation (LBDIE or LBDIDE).
S.E. Mikhailov, Mikhailov, SE
core +1 more source