Results 51 to 60 of about 2,626,634 (290)

Unsteady loss mechanisms in a boundary layer ingestion fan under inlet distortion

Flow
Boundary layer ingestion (BLI) propulsion can improve aircraft aerodynamic efficiency, but also introduces inlet distortion that affects fan flow and stability.
Junyang Yu, Yao Zhao, Yaning Feng, Xiangxin Zhou, Hanbo Jiang   +4 more
doaj   +1 more source

Influences of distributed propulsion system parameters on aerodynamic characteristics of a BLI-BWB UAV

Xibei Gongye Daxue Xuebao, 2021
Focusing on the aerodynamic characteristics of the blended wing body (BWB) aircraft with boundary layer ingestion(BLI) distributed propulsion system; the influences of propulsion system parameters under the condition of cruise and takeoff are studied ...

doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Composite hodographs and inertial oscillations in the nocturnal boundary layer [PDF]

, 2011
In this work the dynamic behaviour of the wind in the nocturnal boundary layer is studied, with a particular focus on systematic behaviour of the near-surface wind.
P. Baas, Wiel, BJH Bas van de, L. van den Brink, A.A.M. Holtslag, Baas, P, van den Brink, L., Wiel, B.J.H., van de, van de Wiel, B.J.H., Wiel, van de, B.J.H., Holtslag, AAM, Holtslag, A.A.M., B. J. H. van de Wiel, Baas, P., Brink, L van den, Brink, van den, L., Brink, L., van den   +15 more
core   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

The flow structure behind vortex generators embedded in a decelerating turbulent boundary layer [PDF]

, 2009
The objective of the present work is to analyse the behaviour of a turbulent decelerating boundary layer under the effect of both passive and active jets vortex generators (VGs).
Braud, Caroline, Godard, Gilles, Cathalifaud, Patricia, Stanislas, Michel   +3 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Optimising Blade Profiles to Extend the Operating Range in BLI Fan Application

International Journal of Turbomachinery, Propulsion and Power
Boundary Layer Ingestion propulsors operate in an adverse aerodynamic environment with high levels of distortion. With the purpose of extending the operating range of transonic fan rotors for BLI applications, in this paper we present an optimisation ...
Andrea Magrini, Ernesto Benini
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source