Results 71 to 80 of about 3,207,541 (303)
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
This article sets out to study creative works of collective memory in contrast to state-backed representations of the past. It takes as examples for analysis the erection of statues of the title hero of Jaroslav Hašek's novel The Good Soldier Svejk in ...
Jakub Grygar
doaj +1 more source
United States, northern border 1878
Index map title: Index map, Joint Series. Shows the United States and Canadian border from the summit of the Rocky Mountains to the northwest angle of the Lake of the Woods. Relief shown by hachures and spot heights. Title from second sheet. First sheet
United States Northern Boundary Commission
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
This document integrates official ground-water data from the United States and Mexico into one data base. These data were exchanged during a series of official meetings held in the offices of the Comisión Internacional de Limites y Aguas and the ...
International Boundary and Water Commission (IBWC)
core
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Digital contact tracing has been claimed as imperative to controlling the spread of COVID-19. However, the state-by-state approach in the United States led to divergences in contact tracing.
Eugene Jang +2 more
doaj
Systematic transition from boundary extension to contraction along an object-to-scene continuum
After viewing a picture of an environment, our memory of it typically extends beyond what was presented—a phenomenon called boundary extension. But sometimes, memory errors show the opposite pattern—boundary contraction—and the relationship between these
Talia Konkle +3 more
core +1 more source

