Results 51 to 60 of about 6,855,519 (278)
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Direct localized boundary-domain integro-differential formulations for physically nonlinear elasticity of inhomogeneous body [PDF]
A static mixed boundary value problem (BVP) of physically nonlinear elasticity for a continuously inhomogeneous body is considered. Using the two-operator Green-Betti formula and the fundamental solution of an auxiliary linear operator, a non-standard ...
Mikhailov, SE
core +4 more sources
On the estimation of the functional
There is considered the functional inf(sup|f (i)(t)), The supremum is taken by i = 0, 1, 2, the infimum is taken by the function set KC2([0, 1]), with boundary conditions f (0) = 1, f'(0) = 1, f (1) = 0, f'(1) = 0.
Gintaras Puriuškis
doaj +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Boundary problem for the singular heat equation
The scheme for solving of a mixed problem with general boundary conditions is proposed for a heat equation \[a(x)\frac{\partial T}{\partial \tau}= \frac{\partial}{\partial x} \left(\lambda(x)\frac{\partial T}{\partial x}\right)\] with coefficient $a(x ...
O.V. Makhnei
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Solution of certain problem with nonlocal boundary condition for one-dimensional wave equation
In this paper, we study a problem with nonlocal boundary condition for one-dimensional wave equation. To prove the solvability of the problem we construct biortogonal basis consisting of eigen- and adjoint-functions of not self adjoint operator.
Elvira E. Gasanova, Ludmila S. Pulkina
doaj +1 more source
DECREASING OF MECHANISMS DYNAMIC LOADING AT THE TRANSIENT STATE
Purpose. It is necessary to select modes of motion to reduce the dynamic loads in the mechanisms. This choice should be made on optimization basis. The purpose of research is to study methods of synthesis regimes of mechanisms and machines motion that ...
V. S. Loveikin, Yu. O. Romasevich
doaj +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source

