Results 21 to 30 of about 161,440 (216)
On a Third-Order Three-Point Boundary Value Problem
International Journal of Mathematics and Mathematical Sciences, 2012 We consider a third-order three-point boundary value problem. We introduce a generalized polynomial growth condition to obtain the existence of a nontrivial solution by using Leray-Schauder nonlinear alternative, then we give an example to illustrate our
A. Guezane-Lakoud +2 more
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FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
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FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
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Dirichlet boundary value problem for Duffing's equation
Electronic Journal of Qualitative Theory of Differential Equations, 2013 We use direct variational method in order to investigate the dependence on parameter for the solution for a Duffing type equation with Dirichlet boundary value conditions.
Piotr Kowalski
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Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
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Mixed algorithm for solving boundary value problem
Computer Assisted Methods in Engineering and Science, 2023 Symbolic computation has been applied to Runge-Kutta technique in order to solve two-point boundary value problem. The unknown initial values are considered as symbolic variables, therefore they will appear in a system of algebraic equations, after the ...
Béla Paláncz, György Popper
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Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
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On Bernoulli boundary value problem
Le Matematiche, 2007 We give a constructive proof of the existence and uniqueness of the solution, under certain conditions, by Picard’s iteration. Moreover Newton’s iteration method is considered for the numerical computation of the solution.
Francesco A. Costabile, Annarosa Serpe
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Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
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