Results 11 to 20 of about 19,015 (122)

Asymptotically accurate error estimates of exponential convergence for the trapezoidal rule

open access: yesDiscrete and Continuous Models and Applied Computational Science, 2021
In many applied problems, efficient calculation of quadratures with high accuracy is required. The examples are: calculation of special functions of mathematical physics, calculation of Fourier coefficients of a given function, Fourier and Laplace ...
Aleksandr A. Belov   +1 more
doaj   +1 more source

Plane problem of discrete environment mechanics

open access: yesПроблеми трибології, 2022
Many engineering problems related to the design of structures and machines, the mathematical description of technological processes, etc., are reduced to the need to solve a plane problem for materials with a significant effect of internal friction on ...
O.V. Bagrii
doaj   +1 more source

On eigenvalues of third order composite type equations with regular boundary value conditions

open access: yesҚарағанды университетінің хабаршысы. Математика сериясы, 2019
In the paper the question about distribution of eigenvalues of third - order composite type equations with regular, more precisely, with periodic boundary value conditions is studied.
N.S. Imanbaev, M.N. Ospanov
doaj   +1 more source

Elastic Equilibrium of Porous Cosserat Media with Double Porosity

open access: yesAdvances in Mathematical Physics, 2016
The static equilibrium of porous elastic materials with double porosity is considered in the case of an elastic Cosserat medium. The corresponding three-dimensional system of differential equations is derived.
Roman Janjgava
doaj   +1 more source

The tri-harmonic Neumann problem

open access: yesҚарағанды университетінің хабаршысы. Математика сериясы, 2018
In this article investigated the tri-harmonic Neumann function for the unit dics. For harmonics functions the Neumann’s boundary problem is well studied and solved under certain conditions through Neumann’s function, sometimes it is also called Green’s ...
S. Burgumbayeva
doaj   +1 more source

On the Combination of the Laplace Transform and Integral Equation Method to Solve the 3D Parabolic Initial Boundary Value Problem

open access: yesAxioms
We consider a two-step numerical approach for solving parabolic initial boundary value problems in 3D simply connected smooth regions. The method uses the Laplace transform in time, reducing the problem to a set of independent stationary boundary value ...
Roman Chapko, Svyatoslav Lavryk
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan   +6 more
wiley   +1 more source

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