Results 31 to 40 of about 119,900,969 (241)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Sufficient conditions of boundedness of L-index and analog of Hayman's Theorem for analytic functions in a ball

Studia Universitatis Babeş-Bolyai. Mathematica, 2018
We generalize some criteria of boundedness of $\mathbf{L}$-index in joint variables for analytic in an unit ball functions. Our propositions give an estimate maximum modulus of the analytic function on a skeleton in polydisc with the larger radii by ...
Andriy Ivanovych Bandura, O. Skaskiv
semanticscholar   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Guide à l'intention du personnel enseignant et de recherche 2003 [PDF]

, 2003
Guide des collections et services offerts par la Direction des bibliothèques de l'Université de ...
Université de Montréal. Direction des bibliothèques
core  

Some improvements of criteria of L-index boundedness in direction

, 2016
A. I. Bandura. Some improvements of criteria of L-index boundedness in direction, Mat. Stud. 47 (2017), 27–32. In this paper, we improve criteria of boundedness of L-index in direction for entire functions in C.
Andriy Ivanovych Bandura
semanticscholar   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

OPEN PROBLEMS FOR ENTIRE FUNCTIONS OF BOUNDED INDEX IN DIRECTION

, 2014
where ∂ 0F (z) ∂b0 = F (z), ∂F (z) ∂b = ∑n j=1 ∂F (z) ∂zj bj = 〈grad F, b〉, ∂ kF (z) ∂bk = ∂ ∂b ( k−1F (z) ∂bk−1 ), k ≥ 2. The least such integer m0 = m0(b) is called the L-index in the direction b ∈ C of the function F (z) and is denoted by Nb(F,L) = m0.
Andriy Ivanovych Bandura, O. Skaskiv
semanticscholar   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source