Results 101 to 110 of about 2,695 (277)

Maximal regularity of the time-periodic Stokes operator on unbounded and bounded domains

Journal of the Mathematical Society of Japan, 2017
We investigate the time-periodic Stokes equations with non-homogeneous divergence data in the whole space, the half space, bent half spaces and bounded domains. The solutions decompose into a well-studied stationary part and a purely periodic part, for which we establish $\mathrm{L}^{p}$ estimates.
MAEKAWA, Yasunori, SAUER, Jonas
openaire   +2 more sources

Dynamic Regulation of Endogenous Transcription Factor Hubs at Single‐Molecule Resolution

Advanced Science, EarlyView.
This study combines single‐molecule microscopy and genome editing to characterize the dynamic behaviors of endogenous oncofusion transcription factor EWS::FLI1 in Ewing sarcoma cells. EWS::FLI1 forms neomorphic hubs that dynamically assemble and dissolve. The hubs are regulated during mitosis, by RNA, and by specific chemicals.
Shawn Yoshida, Yanghao Zhong, Akiko Kumagai, William G. Dunphy, Shasha Chong   +4 more
wiley   +1 more source

Radiation‐Induced Tumor‐Intrinsic LTβR N‐Glycosylation Suppresses Pyroptosis Through TRIM28‐Mediated PCBP2 SUMOylation to Promote Gastric Cancer Radioresistance

Advanced Science, EarlyView.
Radiotherapy triggers LTβR N‐glycosylation, enhancing its overall protein stability and nuclear retention. This accumulation drives TRIM28‐mediated PCBP2 SUMOylation, suppressing pyroptosis and conferring gastric cancer radioresistance. Therapeutically, a targeted nanoplatform (cRGD‐Lipo@EMD) effectively disrupts this regulatory axis, offering a highly
Weijie Zang, Yunlong Ji, Chunwang Zhou, Xiwen Li, Zhuang Lu, Guangze Zhang, Yu Chen, Wanjiang Xue, Yilin Hu   +8 more
wiley   +1 more source

D-Cyclic Operators: A Unified Framework for Cyclicity in Linear Dynamics

Mathematics
We introduce the notion of D-cyclicity for bounded linear operators on a separable infinite-dimensional complex Banach space, which unifies several classical cyclicity concepts through appropriate choices of D⊂C.
B. Sanooj, P. B. Vinod Kumar
doaj   +1 more source

Interacting Parallel Fluidic Hysterons

Advanced Science, EarlyView.
The parallel coupling of fluidic hysterons is introduced, establishing advanced functionalities in inflatable soft systems. A pressure–volume framework reveals how preset volumes Δv∗${\Delta }v^*$ tune nonlinear interactions between hysterons and actuation sequences without changing architecture. Experiments validate the predictions, opening new routes
Katrien Stinissen, Franco Nicolas Piñan Basualdo, Benjamin Gorissen   +2 more
wiley   +1 more source

Neuron‐Derived MIF Engages VCAM1 to Fuel a Self‐Amplifying CXCL8 Loop That Drives Perineural Invasion and Metastasis in Gastric Cancer

Advanced Science, EarlyView.
Neuron‐derived MIF binds VCAM1 on gastric cancer cells and activates ERK/STAT3 signaling, leading to CXCL8 transcription and secretion. Tumor‐derived CXCL8 subsequently stimulates neuronal CXCR2 to enhance MIF production, establishing a self‐amplifying MIF–VCAM1–CXCL8 positive‐feedback loop that promotes perineural invasion, tumor progression, and ...
Xunjun Li, Zhongya Zhai, Haiyi Yu, Renjie Qiu, Fengyu Li, Luxi Xiao, Boxi Huang, Huiying Liu, Jiayong He, Bowen Cai, Jiawen Chen, Jiang Yu, Guoxin Li, Tao Chen   +13 more
wiley   +1 more source

Existence of weak solutions for nonlinear elliptic systems on $R^N$

Electronic Journal of Differential Equations, 2006
In this paper, we consider the nonlinear elliptic system $$displaylines{ -Delta_pu=a(x)|u|^{p-2}u-b(x)|u|^alpha|v|^eta v+f,cr -Delta_qv=-c(x)|u|^alpha |v|^eta u + d(x) |v|^{q-2}v +g ,cr lim_{|x|oinfty}u=lim_{|x|oinfty}v=0quad u,v>0 }$$ on a ...
Eada A. El-Zahrani, Hassan M. Serag
doaj  

Biomimetic Macrophage Cell Membrane‐Based Nanoparticles for Effective Treatment of Glioblastoma Through Boron Neutron Capture Therapy Combined With Immunotherapy

Advanced Science, EarlyView.
ABSTRACT Glioblastoma multiforme (GBM) remains largely incurable due to the blood‐brain barrier (BBB) and immunosuppressive microenvironment. While boron neutron capture therapy (BNCT) selectively eradicates tumor cells via 10B(n, α)‐7Li reactions, its clinical potential in GBM is unrealized because of the suboptimal pharmacokinetics of conventional ...
Jiawen Chen, Haoyu You, Hefa Huang, Huihui Chai, Ruize Zhu, Yun Guan, Qisheng Tang, Tianwen Li, Shan Jiang, Houshi Xu, Peng Wang, Yue Wang, Maoyuan Sun, Beining Liu, Zhen Li, Yulai Zeng, Weiqiu Ping, Yanlin Teng, Songlin Yan, Qinghui Li, Long Gu, Tao Sun, Zhifeng Shi   +22 more
wiley   +1 more source

The F-functional calculus for unbounded operators

, 2018
\ua9 Springer Nature Switzerland AG 2018. Similar to the S-functional calculus, we can also extend the F-functional calculus to unbounded operators by suitably transforming the operator and the function and then applying the theory for bounded operators.
Colombo F, Kimsey DP, Gantner J
core   +4 more sources

Perturbation of Weyl’s Theorems for Unbounded  Upper Triangular Operator Matrices

Ibn Al-Haitham Journal for Pure and Applied Sciences
Let  be an upper triangular operator matrix which is unbounded and defined on , where  is infinite dimensional Hilbert space. This paper is concerned with new spectral properties which defined to other bounded operators.
Dalia S. Ali, Buthainah A.A. Ahmed
doaj   +1 more source