Results 141 to 150 of about 1,242,956 (315)

Group Invariant Bounded Linear Functions on Dedekind Complete Totally\n Ordered Riesz Spaces [PDF]

, 2017
George Chailos
openalex   +1 more source

Bounded rational functions

, 2022
Ce manuscrit commence l’étude des fonctions rationnelles bornées, qui sont une extension naturelle des fonctions régulues et sont liées à la normalisation. Elles sont aussi liées aux anneaux de fonctions bornées (ou anneau d’holomorphie) et elles fournissent les exemples les plus simples de fonctions non continues à plusieurs variables.On montre qu’il ...
openaire   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Convergence of product integration rules for functions with interior and endpoint singularities over bounded and unbounded intervals [PDF]

, 1986
D. S. Lubinsky, Avram Sidi
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Bounded univalent functions [PDF]

Transactions of the American Mathematical Society, 1942
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Fast rates for empirical risk minimization over càdlàg functions with bounded sectional variation norm [PDF]

, 2019
Aurélien Bibaut, Mark J. van der Laan
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

On Error Bound Moduli for Locally Lipschitz and Regular Functions [PDF]

, 2016
Minghua Li, Kaiwen Meng, Xiaoqi Yang
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Almost bounded functions [PDF]

Transactions of the American Mathematical Society, 1955
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