Results 171 to 180 of about 1,242,956 (315)
FEBS Open Bio, EarlyView.CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
Existence of $psi$-bounded solutions for a system of differential equations
Electronic Journal of Differential Equations, 2004 In this article, we present a necessary and sufficient condition for the existence of solutions to the linear nonhomogeneous system $x'=A(t)x + f(t)$. Under the condition stated, for every Lebesgue $Psi$-integrable function $f$ there is at least one $Psi$
Aurel Diamandescu
doaj
Uniform Convergence of Double Fourier-Legendre series of Functions of Bounded Generalized Variation [PDF]
, 2012 Ушанги Гогинава
openalex +1 more source
FEBS Open Bio, EarlyView.CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama +7 more
wiley +1 more source
Variability Regions for Bounded Analytic Functions with Applications to Families Defined by Subordination [PDF]
, 1980 Yusuf Abu-Muhanna, Thomas H. MacGregor
openalex +1 more source
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
Power bounded weighted composition operators on function spaces defined by local properties [PDF]
, 2018 Thomas Kalmes
openalex +1 more source
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
FEBS Open Bio, EarlyView.We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
Ramifications of generalized Feller theory. [PDF]
J Evol EquCuchiero C, Möllmann T, Teichmann J.
europepmc +1 more source