Results 71 to 80 of about 171,423 (283)

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Instructional Design to Promote Translingual Practices in an English First Additional Language Context

open access: yesJournal of Languages and Language Teaching, 2023
Languages are not set, autonomous, bounded entities whose nature cannot be disrupted; they are flexible entities that can be reformed, re-arranged and recreated to fit into new contexts of communication.
Kufakunesu Zano, Vimbai Mbirimi-Hungwe
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Deriving bounded tone with layered feet in Harmonic Serialism: The case of Saghala

open access: yesGlossa, 2017
This paper proposes an approach to bounded tone shift and spread as found in Bantu languages. Its core intuition is that the bounding domain is delimited by foot structure.
Jeroen Breteler
doaj   +2 more sources

Retreat bounded picture languages

open access: yesTheoretical Computer Science, 1994
AbstractA well-known string-encoding of 2D pictures is to use the picture alphabet π = {u, d, r, l}, where u (d, r, and l) means “draw a unit-line by moving the pen up (down, right, and left) from the current point”. A word over π is k-retreat-bounded (k⩾0) if it describes a picture in such a manner that the maximum distance of left-moves, ignoring up-
openaire   +2 more sources

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Almost Every Simply Typed Lambda-Term Has a Long Beta-Reduction Sequence [PDF]

open access: yesLogical Methods in Computer Science, 2019
It is well known that the length of a beta-reduction sequence of a simply typed lambda-term of order k can be huge; it is as large as k-fold exponential in the size of the lambda-term in the worst case.
Kazuyuki Asada   +3 more
doaj   +1 more source

Left-derivation bounded languages

open access: yesJournal of Computer and System Sciences, 1974
Left-derivation bounded languages are defined as those languages defined from context-free grammars by placing a bound on the number of nonterminals appearing in left-derivations. These languages are generated by left-derivation bounded grammars and form a full AFL not closed under reversal.
openaire   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

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