Results 121 to 130 of about 15,568 (347)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Economics and psychology.Perfect rationality versus bounded rationality

open access: yes
Classical mathematical algorithms often fail to identify in time when the international financial crises occur although, as the classical theory of choice would suggest, the economic agents are rational and the markets are or should be efficient and ...
Schilirò, Daniele
core  

The Weak Rationality Principle in Economics [PDF]

open access: yes
The weak rationality principle is not an empirical statement but a heuristic rule how to proceed in social sciences. It is a necessary ingredient of any understanding’ social science in the Weberian sense. In this paper, first this principle and its role
Gebhard Kirchgässner
core  

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Trust Under Bounded Rationality: Exploring Human-AI Interaction in Decision-Making Through Large Language Models

open access: yesSAGE Open
This study investigates the role of artificial intelligence (AI) and large language models (LLMs) within Simon’s bounded rationality framework, focusing on factors such as preferences, competence, learning, and persuasion that influence decision-makers ...
Waleed Almutairi, Ibrahim Almatrodi
doaj   +1 more source

The Simonian bounded rationality hypothesis and the expectation formation mechanism

open access: yes
. In the 1980s and at beginning of the 1990s the debate on expectation formation mechanism was dominated by the rational expectation hypothesis. Later on, more interest was directed towards alternative approaches to expectations analysis, mainly based on
Kowalski, Tadeusz
core  

Econometric Explorations on Bounded Rationality: The Case of Job Changing Behavior [PDF]

open access: yes
In this paper we question the hypothesis of full rationality in the context of job changing behaviour, via simple econometric explorations on microdata drawn from WHIP (Worker Histories Italian Panel).
Bruno Contini, Matteo Morini
core  

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

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