Results 111 to 120 of about 3,031,442 (296)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Behavior at infinity of psi-evanescent solutions to linear differential equations

open access: yesElectronic Journal of Differential Equations, 2010
In this article we present some necessary and sufficient conditions for the existence of $psi$-evanescent solution of the nonhomogeneous linear differential equation $x'=A(t)x+f(t)$, which is related to the notion of $psi$-ordinary dichotomy for the ...
Pham Ngoc Boi
doaj  

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Mostly oscillation for a system of half linear neutral differential equations of the second order with several arguments

open access: yesمجلة بغداد للعلوم
This paper studies the oscillation properties and asymptotic behavior of all solutions of the 2×2 system of second-order half-linear neutral differential equations. Four results are obtained in this research.
Noor Abdulamer Abdulkarem   +3 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Bounded solutions in epidemic models governed by semilinear parabolic equations with general semilinear incidence rates

open access: yesҚарағанды университетінің хабаршысы. Математика сериясы
The transmission mechanisms of most infectious diseases are generally well understood from an epidemiological standpoint. To mathematically and quantitatively characterize the spread of these diseases, various classical epidemic models-such as the SIR ...
A. Ashyralyev   +2 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Simon's Bounded Rationality. Origins and use in economic theory [PDF]

open access: yes
The paper aims to show how Simon's notion of bounded rationality should be interpreted in the light of its connection with artificial intelligence. This connection points out that bounded rationality is a highly structured concept, and sheds light on ...
Fiori Stefano
core  

Uniformly boundedness of a class of non-linear differential equations of third order with multiple deviating arguments

open access: yesCubo, 2012
This paper deals with a certain third-order non-linear differential equation with multiple deviating arguments. Some sufficient conditions are set up for all solutions and their derivatives to be uniformly bounded.En este artículo se estudia un tipo de ...
Cemil Tunc, Hilmi Ergören
doaj  

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