Results 101 to 110 of about 3,031,442 (296)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Pairings, duality, amenability and bounded cohomology

open access: yes, 2012
We give a new perspective on the homological characterisations of amenability given by Johnson and Ringrose in the context of bounded cohomology and by Block and Weinberger in the context of uniformly finite homology.
Wright, Nick   +2 more
core   +1 more source

Structural stability and robustness to bounded rationality

open access: yes, 2000
The introduction of a small amount of bounded rationality into a model sometimes has little effect, and sometimes has a dramatic impact on predicted behavior.
Canning, David, Anderlini, Luca
core   +1 more source

Bounded and Periodic Solutions of Integral Equations

open access: yesCubo, 2012
In this paper we introduce a new method for obtaining boundedness of solutions of integral equations. From the integral equation we form an integrodifferential equation by computing x' + kx to which we apply a Liapunov functional.
T. A Burton, Bo Zhang
doaj  

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Convex Approximation of Bounded Rational Equilibria [PDF]

open access: yes
In this paper, we consider the existence of a sequence of convex sets that has an approximation property for the equilibrium sets in the bounded rational environments.
Hiromi Azuma, Yusuke Miyazaki
core  

Decay of Strong Solutions for 4D Navier-Stokes Equations Posed on Lipschitz Domains

open access: yesAdvances in Mathematical Physics, 2018
Initial-boundary value problems for 4D Navier-Stokes equations posed on bounded and unbounded 4D parallelepipeds were considered. The existence and uniqueness of regular global solutions on bounded parallelepipeds and their exponential decay as well as ...
N. A. Larkin
doaj   +1 more source

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