Results 21 to 30 of about 468,918 (185)

On ordered Λ-bounded variation [PDF]

open access: yesProceedings of the American Mathematical Society, 1990
An example is given of a continuous real function that is of ordered Λ \Lambda -bounded variation but not of Λ \Lambda -bounded variation. No special assumptions on Λ \Lambda are required.
openaire   +2 more sources

Functions of locally bounded variation on Wiener spaces

open access: yes, 2014
We introduce the concept of functions of locally bounded variation on abstract Wiener spaces and study their properties. Some nontrivial examples and applications to stochastic analysis are also discussed.Comment: 20 pages, accepted for ...
Hino, Masanori
core   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

A chain rule formula in BV and applications to conservation laws

open access: yes, 2010
In this paper we prove a new chain rule formula for the distributional derivative of the composite function $v(x)=B(x,u(x))$, where $u:]a,b[\to\R^d$ has bounded variation, $B(x,\cdot)$ is continuously differentiable and $B(\cdot,u)$ has bounded variation.
De Cicco V.   +2 more
core   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

On functions of bounded p-variation

open access: yesJournal of Mathematical Analysis and Applications, 2009
AbstractWe obtain estimates of the total p-variation ...
Martin Lind, Viktor Kolyada
openaire   +2 more sources

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

open access: yesFEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring   +6 more
wiley   +1 more source

The maximal variation of a bounded martingale [PDF]

open access: yesAdvances in Applied Probability, 1977
Let $$\chi _0^n = \left\{ {X_t } \right\}_0^n $$ be a martingale such that 0≦Xi≦1;i=0, …,n. For 0≦p≦1 denote by ℳ the set of all ...
Jean-François Mertens   +3 more
openaire   +2 more sources

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