Results 41 to 50 of about 61,672 (299)

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Model Reduction of LPV Control with Bounded Parameter Variation Rates [PDF]

, 2006
This paper proposes a reduced-order controller of linear parameter varying systems. The parameters are available for measurement while their ranges and rates of variation are assumed to be bounded.
Riyanto, T. Bambang, Widowati, Widowati
core  

Inclusions of Multivariable Bounded Variation Functions

Journal of Function Spaces
In this paper, some characterizations of the embeddings Λ∗BVp⊆∗Hqω and Φ∗BV⊆BV∗q:δ are given. The results presented here generalize and extend earlier embedding results between related classes of functions of bounded variation.
Batoul S. Mortazavi-Samarin, Mehdi Rostami   +1 more
doaj   +1 more source

On functions of bounded variation [PDF]

Mathematical Proceedings of the Cambridge Philosophical Society, 2016
AbstractThe recently introduced concept of ${\mathcal D}$-variation unifies previous concepts of variation of multivariate functions. In this paper, we give an affirmative answer to the open question from [20] whether every function of bounded Hardy–Krause variation is Borel measurable and has bounded ${\mathcal D}$-variation.
Aistleitner, Christoph, Pausinger, Florian, Svane, Anne Marie, Tichy, Robert   +3 more
openaire   +3 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

BV Solutions to Evolution Inclusion with a Time and Space Dependent Maximal Monotone Operator

Mathematics
This paper deals with the research of solutions of bounded variation (BV) to evolution inclusion coupled with a time and state dependent maximal monotone operator. Different problems are studied: existence of solutions, unicity of the solution, existence
Charles Castaing, Christiane Godet-Thobie, Manuel D. P. Monteiro Marques   +2 more
doaj   +1 more source

Bounded variation of functions defined on a convex and compact set in the plane

Arab Journal of Basic and Applied Sciences, 2023
In this paper, the variation of functions has been defined, whose domain is a convex and compact set in the plane. Furthermore, in addition to presenting properties that satisfy this variation, the vector space formed by functions with finite variation ...
Mireya Bracamonte, Juan Tutasi
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

On the Lp-differentiability of certain classes of functions [PDF]

, 2014
We prove the $L^p$-differentiability at almost every point for convolution products on $R^d$ of the form $K*\mu$, where $\mu$ is bounded measure and $K$ is a homogeneous kernel of degree $1-d$.
Crippa, Gianluca, Crippa G., Gianluca Crippa, Bianchini, Stefano, Alberti G., Stefano Bianchini, Alberti, Giovanni, Bianchini S.   +7 more
core   +1 more source

New Information Inequalities in Terms of Variational Distance and its Application

Journal of New Results in Science, 2016
In this work, new information inequalities are obtained and characterized on new generalized f- divergence (introduced by Jain and Saraswat (2012)) in terms of the Variational distance and these inequalities have been taken for evaluating some new ...
K. C. Jain, Praphull Chhabra
doaj