Results 61 to 70 of about 61,672 (299)
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
On Functions of Bounded (p,k)-Variation
Journal of Function Spaces and Applications, 2012 We introduce and study the concept of (p,k)-variation ...
N. Merentes, S. Rivas, J. L. Sanchez
doaj +1 more source
Continuous dependence results for set-valued measure differential problems
Electronic Journal of Qualitative Theory of Differential Equations, 2015 We discuss existence and continuous dependence properties of solutions set of measure differential inclusions \begin{equation}\label{(1)} \begin{split} dx(t)& \in G(t, x(t)) d\mu(t),\\ x(0)& = x_0. \end{split} \end{equation} where $G \colon [0,1] \times \
Bianca Satco
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
On ordered harmonic bounded variation
, 1980 An example is given of a continuous real function that is of ordered harmonic bounded variation but not of harmonic bounded variation.
C. L. Belna
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Computable Jordan Decomposition of Linear Continuous Functionals on $C[0;1]$ [PDF]
Logical Methods in Computer Science, 2014 By the Riesz representation theorem using the Riemann-Stieltjes integral, linear continuous functionals on the set of continuous functions from the unit interval into the reals can either be characterized by functions of bounded variation from the unit ...
Klaus Weihrauch, Tahereh Jafarikhah
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Some Landau Type Inequalities for Functions whose Derivatives are of locally bounded variation
, 2005 Some inequalities of the Landau type for functions whose derivatives are of locally bounded variation are pointed ...
Dragomir, Sever S, Barnett, Neil S
core