Results 81 to 90 of about 55,236 (257)

New Generalized Inequalities for Functions of Bounded Variation

open access: yesCumhuriyet Science Journal, 2018
In this paper, firstly we obtain some generalized trapezoid and midpointtype inequalities for functions of bounded variation using two new generalized identitiesfor Riemann-Stieltjes integrals. Then quadrature formula is also provided.
Mehmet Zeki Sarıkaya, Hüseyin Budak
doaj   +1 more source

On system operators with variation bounding properties

open access: yesAutomatica
The property of linear discrete-time time-invariant system operators mapping inputs with at most $k-1$ sign changes to outputs with at most $k-1$ sign changes is investigated. We show that this property is tractable via the notion of $k$-sign consistency in case of the observability/controllability operator, which as such can also be used as a ...
Christian Grussler   +2 more
openaire   +2 more sources

Space-time integral currents of bounded variation. [PDF]

open access: yesCalc Var Partial Differ Equ, 2023
Rindler F.
europepmc   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Measure integral inclusions with fast oscillating data

open access: yesElectronic Journal of Differential Equations, 2015
We prove the existence of regulated or bounded variation solutions, via a nonlinear alternative of Leray-Schauder type, for the measure integral inclusion $$ x(t) \in \int_0^t F(s, x(s)) \,du(s), $$ under the assumptions of regularity, respectively
Bianca-Renata Satco
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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