Results 131 to 140 of about 18,644 (317)
The investigation given right here is part of a literature review on mathematical models that apply analytical mathematics. The present work focuses on the COVID-19 model, which incorporates optimum control variables previously investigated and ...
Lukman Hakim, Lilis Widayanti
doaj +1 more source
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
The boundedness of operators in Muckenhoupt weighted Morrey spaces via\n extrapolation techniques and duality [PDF]
Marcel Rosenthal +1 more
openalex +1 more source
Boundedness in Asymmetric Oscillations
The equation \(x''+ ax^+- bx^-= f(t)\) is studied where \(f(t)\) is a \(2\pi\)-periodic function, \(a\) and \(b\) are positive constants such that \(a\neq b\). It is shown that under some assumptions, all solutions to the equation are bounded, more precisely, if \(x(t)\) is a solution to the equation, then it is defined for all \(t\in \mathbb{R}\), and
openaire +2 more sources
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Boundedness and global solvability for a chemotaxis-haptotaxis model with p-Laplacian diffusion
Changchun Liu, Pingping Li
openalex +2 more sources
Global existence and uniform boundedness in a chemotaxis model with signal-dependent motility [PDF]
Jie Jiang, Philippe Laurençot
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Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source

