Results 81 to 90 of about 1,414,908 (321)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
On a class of p-valent close-to-convex functions of order β and type α
International Journal of Mathematics and Mathematical Sciences, 1988 Let S(A,B,p,α) denote the class of functions g(z)=zp+∑n=p+1∞bnzn analytic in the unit disc U={z:|z|
M. K. Aouf
doaj +1 more source
Mathematics, 2019 In this paper, new refinements and improvements of Jordan’s and Kober’s inequalities are presented. We give new polynomial bounds for the s i n c ( x ) and cos ( x ) functions based on the interpolation and approximation ...
Lina Zhang, Xuesi Ma
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
AIMS Mathematics, 2020 In this study, we introduce a new general identity for n th order differentiable functions. Also, we establish some new inequalities regarding general perturbed trapezoid inequality for the functions whose the absolute values of n th derivatives are ...
Zitong He +4 more
doaj +1 more source
Cosmodynamics: energy conditions, Hubble bounds, density bounds, time and distance bounds [PDF]
Classical and Quantum Gravity, 2008 We refine and extend a programme initiated by one of the current authors [Science 276 (1997) 88; Phys. Rev. D56 (1997) 7578] advocating the use of the classical energy conditions of general relativity in a cosmological setting to place very general bounds on various cosmological parameters.
Cattoen, Celine, Visser, Matt
openaire +2 more sources
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Conditional bounds for the least quadratic non-residue and related problems [PDF]
, 2016 This paper studies explicit and theoretical bounds for several interesting quantities in number theory, conditionally on the Generalized Riemann Hypothesis. Specifically, we improve the existing explicit bounds for the least quadratic non-residue and the
Lamzouri, Youness +2 more
core
Proceedings of the American Mathematical Society, 2007 We give a short proof of the fact that bounded earthquakes of the unit disk induce quasisymmetric maps of the unit circle. By a similar method, we show that symmetric maps are induced by bounded earthquakes with asymptotically trivial measures.
openaire +2 more sources
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source