Results 81 to 90 of about 16,644 (310)

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Entropic Bounds on the Average Length of Codes with a Space

open access: yesEntropy
We consider the problem of constructing prefix-free codes in which a designated symbol, a space, can only appear at the end of codewords. We provide a linear-time algorithm to construct almost-optimal codes with this property, meaning that their average ...
Roberto Bruno, Ugo Vaccaro
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Short barcodes for next generation sequencing. [PDF]

open access: yesPLoS ONE, 2013
We consider the design and evaluation of short barcodes, with a length between six and eight nucleotides, used for parallel sequencing on platforms where substitution errors dominate.
Katharina Mir   +3 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

On the upper bound of the size of the r-cover-free families

open access: yes, 1994
Let T (r; n) denote the maximum number of subsets of an n-set satisfying the condition in the title. It is proved in a purely combinatorial way, that for n sufficiently large log 2 T (r; n) n 8 \Delta log 2 r r 2 holds. 1.
Miklós Ruszinko, Ruszinkó, Miklós
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

The Divisible Code Bound Revisited

open access: yesJournal of Combinatorial Theory, Series A, 2001
A linear code over \(\text{GF}(q)\) is called divisible if the weights of its codewords have a common divisor \(\Delta > 1\). If \(\Delta\) is relatively prime to \(q\), the code is essentially a \(\Delta\)-fold replicated code. So the case of interest is when the characteristic \(p\) divides \(\Delta\). The author gives a new, character-free proof for
openaire   +1 more source

Upper bounds for constant-weight codes

open access: yes, 2000
Let A(n,d,w) denote the maximum possible number of codewords in an (n,d,w) constant-weight binary code. We improve upon the best known upper bounds on A(n,d,w) in numerous instances for n⩽24 and d⩽12, which is the parameter range of existing ...
Agrell, Erik   +6 more
core   +1 more source

A comparison of distance bounds for quasi-twisted codes

open access: yes, 2021
Spectral bounds on the minimum distance of quasi-twisted codes over finite fields are proposed, based on eigenvalues of polynomial matrices and the corresponding eigenspaces.
Ezerman, Martianus Frederic   +5 more
core   +1 more source

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