Results 51 to 60 of about 74,760 (269)

Examining the Validity of Wagner's Law versus Keynesian Hypothesis: Evidence from Turkey's Economy

open access: yesScientific Annals of Economics and Business, 2019
The direction of the causality relationship between public expenditures and economic growth is one of the most controversial issues of the literature, which also causes great disagreements in the design process of economic policies.
Özcan Karahan, Olcay Çolak
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Information-Theoretic Generalization Bounds for Meta-Learning and Applications

open access: yesEntropy, 2021
Meta-learning, or “learning to learn”, refers to techniques that infer an inductive bias from data corresponding to multiple related tasks with the goal of improving the sample efficiency for new, previously unobserved, tasks.
Sharu Theresa Jose, Osvaldo Simeone
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Public debt and inflation nexus in Nigeria: An ARDL bounds test approach

open access: yesCogent Economics & Finance, 2021
Inflationary tendencies of public debt have been the cause of an unsettling debate among policymakers in Nigeria. Using the autoregressive distributed lag (ARDL) framework, this study attempts to investigate the impact of total public debt on inflation ...
Akingbade U. Aimola   +1 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Balance-Of-Payments-Constrained Growth Model: Empirical Evidence from Malaysia

open access: yesInternational Journal of Management Studies, 2005
Applying cointegration approach, the present study aims to examine the validity of the Harrod Thirlwall balance-of-payments-constrained growth model in Malaysia.
Tuck Cheong Tang
doaj  

Lower bounds for linear degeneracy testing [PDF]

open access: yesJournal of the ACM, 2004
In the late nineties, Erickson proved a remarkable lower bound on the decision tree complexity of one of the central problems of computational geometry: given n numbers, do any r of them add up to 0? His lower bound of Ω( n ⌈ r
Nir Ailon, Bernard Chazelle
openaire   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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