Results 71 to 80 of about 713,380 (292)
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Kissing numbers and transference theorems from generalized tail bounds [PDF]
We generalize Banaszczyk's seminal tail bound for the Gaussian mass of a lattice to a wide class of test functions. From this we obtain quite general transference bounds, as well as bounds on the number of lattice points contained in certain bodies.
Miller, Stephen D. +1 more
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
This paper demonstrates a significant, long-running relationship between stock prices and domestic interest rates in Turkey’s financial markets for the period of 2001 M1 – 2017 M4.
Turgut Tursoy
doaj +1 more source
k2U: A General Framework from k-Point Effective Schedulability Analysis to Utilization-Based Tests
To deal with a large variety of workloads in different application domains in real-time embedded systems, a number of expressive task models have been developed.
Chen, Jian-Jia +2 more
core +1 more source
Testing the bounds on quantum probabilities [PDF]
9 pages ...
Filipp, Stefan, Svozil, Karl
openaire +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Analysis of Inflation Dynamics in Post-Communist Economies : The Case of Uzbekistan
This paper seeks to investigate the short-run and long-run relationship between price level and monetary, non-monetary and external factors of inflation in Uzbekistan, from January 2016 to August 2025.
Elyor Davlatov +2 more
doaj +1 more source
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Elitism Levels Traverse Mechanism For The Derivation of Upper Bounds on Unimodal Functions [PDF]
In this article we present an Elitism Levels Traverse Mechanism that we designed to find bounds on population-based Evolutionary algorithms solving unimodal functions. We prove its efficiency theoretically and test it on OneMax function deriving bounds c{
Ter-Sarkisov, Aram
core +1 more source

