Results 81 to 90 of about 713,380 (292)

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Influence of Lipschitz bounds on the speed of global optimization

Technological and Economic Development of Economy, 2012
Global optimization methods based on Lipschitz bounds have been analyzed and applied widely to solve various optimization problems. In this paper a bound for Lipschitz function is proposed, which is computed using function values at the vertices of a ...
Remigijus Paulavičius, Julius Žilinskas   +1 more
doaj   +1 more source

Temporal quantum correlations and Leggett-Garg inequalities in multi-level systems

, 2014
We show that the quantum bound for temporal correlations in a Leggett-Garg test, analogous to the Tsirelson bound for spatial correlations in a Bell test, strongly depends on the number of levels $N$ that can be accessed by the measurement apparatus via ...
Budroni, Costantino, Emary, Clive
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Upper Bound Solutions of Ring Compression Test

Procedia Engineering, 2013
El presente trabajo aborda una particularización del proceso de forja, estudiando la deformación de un anillo. El conformado plástico se realiza mediante el empleo del Teorema del Límite Superior y siguiendo el modelo de Bloques Rígidos Triangulares para calcular la carga mínima necesaria para deformar plásticamente la pieza.
Martín-Fernández, Francisco de Sales, Sevilla-Hurtado, Lorenzo, Camacho López, Ana María, Sebastián Pérez, Miguel Ángel   +3 more
openaire   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Impact of tax revenue on economic growth: A study from Cambodia

Ho Chi Minh City Open University Journal of Science - Economics and Business Administration
The study examines the impact of tax revenue on economic growth in Cambodia from 1994 to 2022. The Autoregressive Distributed Lag (ARDL) method is applied to test the cointegration between variables.
Kong Chantha
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Macroeconomic drivers of chemical industry stock prices: a comparative analysis of US and German markets

Cogent Economics & Finance
This study investigates the impact of macroeconomic factors—inflation, interest rates, exchange rates, money supply, and crisis events—on chemical industry index prices in the US and Germany, using the Autoregressive Distributed Lag (ARDL) model.
Khurshid Khudoykulov, Abdukodir Rasulov, Petros Golitsis, Pavlos Gkasis   +3 more
doaj   +1 more source