Results 81 to 90 of about 54,042 (173)

Bovine coronavirus nonstructural protein ns2 is a phosphoprotein

open access: yesVirology, 1991
To investigate the nature of the bovine coronavirus (BCV) ns2 protein, the gene encoding this protein was cloned and was expressed as a beta-galactosidase fusion protein. Antiserum raised against this protein reacted specifically with BCV-infected fixed cells in indirect immunofluorescence microscopy and precipitated an in vitro synthesized product ...
Cox, Graham J.   +2 more
openaire   +2 more sources

ZFP36L1 Enhances Microglial Ferroptosis in Ischemic Stroke by Reducing FTO‐Mediated N6‐Methyladenosine Demethylation of ACSL1 mRNA

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Microglia play an important role in ischemic stroke (IS). However, the molecular regulatory mechanisms underlying microglial ferroptosis in IS remain incompletely understood. In this study, blood samples were collected from 20 IS patients and 15 healthy volunteers.
Ai‐Xia Song   +7 more
wiley   +1 more source

Harnessing Aggregation‐Induced Emission for Advanced Disease Diagnosis: Mechanisms, Strategies and Future Perspectives

open access: yesMedicine Bulletin, EarlyView.
The figure was created in BioRender.com. ABSTRACT Accurate and early diagnosis remains a key challenge in modern disease management. Conventional diagnostic methods often suffer from limitations in sensitivity, spatial resolution, and practical usability.
Zizhuo Du   +10 more
wiley   +1 more source

Heterologous protein secretion in Lactococcus lactis: a novel antigen delivery system

open access: yesBrazilian Journal of Medical and Biological Research, 1999
Lactic acid bacteria (LAB) are Gram-positive bacteria and are generally regarded as safe (GRAS) organisms. Therefore, LAB could be used for heterologous protein secretion and they are good potential candidates as antigen delivery vehicles.
Langella P., Le Loir Y.
doaj  

Women in space: A review of known physiological adaptations and health perspectives

open access: yesExperimental Physiology, EarlyView.
Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford   +4 more
wiley   +1 more source

Polarized Entry of Bovine Coronavirus in Epithelial Cells [PDF]

open access: yes, 1995
Epithelial cells are highly polarized cells divided into an apical and a basolateral plasma membrane. The two domains are composed of a distinct set of proteins and lipids. Concerning virus infection of epithelial cells, the polarity of host cell receptor distribution defines the domain from which infection may be mediated.
B, Schultze, G, Herrler
openaire   +2 more sources

Assessment of faecal calprotectin in neonatal calf diarrhoea using a human ELISA kit: Associations with faecal score and serum biochemical markers

open access: yesVeterinary Record Open, Volume 13, Issue 2, December 2026.
Abstract Background Diarrhoea in newborn calves, which occurs in the first month of life and is caused by various pathogens, poses a significant threat to livestock industries. Therefore, timely diagnosis of enteritis in calves can be advantageous. Objective This study aimed to determine the efficacy of faecal calprotectin as a biomarker indicating ...
Narges Lotfalizadeh   +3 more
wiley   +1 more source

Multimerization of a rationally designed nanobody for enhanced avidity toward Aβ42 oligomers

open access: yesProtein Science, Volume 35, Issue 9, September 2026.
Abstract Alzheimer's disease affects tens of millions of people worldwide and is associated with the self‐assembly of the Aβ42 peptide into amyloid aggregates. Among the species formed during this process, soluble oligomeric intermediates are the most closely linked to neurotoxicity and are therefore an attractive target for both therapeutic and ...
Magdalena Nowinska   +3 more
wiley   +1 more source

Molecular and Serological Detection of Bovine Coronaviruses in Marmots (Marmota marmota) in the Alpine Region

open access: yesViruses
In this study, virological surveillance focused on coronaviruses in marmots in the Alpine region in 2022, captured as part of a population control reduction program in the Livigno area.
Ana Moreno   +16 more
doaj   +1 more source

Estimating the Economic Impact of Neonatal Calf Diarrhea Agents With Decision Tree Analysis and the Monte Carlo Simulation Model

open access: yesVeterinary Medicine and Science, Volume 12, Issue 5, September 2026.
This study aims to determine the economic impacts of the major agents causing diarrhoea in newborn calves using Monte Carlo simulation and decision tree analysis. According to the study results, the cost per animal was $13.7 for healthy calves without diarrhoea.
Mehmet Küçükoflaz   +7 more
wiley   +1 more source

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