Hypoxia enhances secretion of matrix metalloproteinases in bovine dermal fibroblasts: an in vitro approach to bovine digital dermatitis [PDF]
Dermal fibroblasts are of great importance in skin homeostasis. They are responsible for the synthesis and remodelling of extracellular proteins by the way of synthesis of some specific kind of Matrix Metalloproteinases (MMPs). Imbalance between MMPs and
Ahmet Akkoc +2 more
doaj +9 more sources
Detection of Treponema spp. in bovine digital dermatitis in the Amazon biome, Brazil [PDF]
: Bovine digital dermatitis (BDD) is a polybacterial claw disease that is endemic to dairy cattle kept in loose house systems, and treponemas are the main bacteria implicated in this disease.
Henrique A. Bomjardim +7 more
doaj +6 more sources
Metabolic Footprint of Treponema phagedenis and Treponema pedis Reveals Potential Interaction Towards Community Succession and Pathogenesis in Bovine Digital Dermatitis [PDF]
Bovine digital dermatitis (BDD) is a cattle infection causing hoof lesions and lameness, with treponemes as key pathogens. We analyzed the metabolic activity of Treponema phagedenis and Treponema pedis using gas chromatography–mass spectrometry for ...
Hector M. Espiritu +6 more
doaj +4 more sources
Altered microbiomes in bovine digital dermatitis lesions, and the gut as a pathogen reservoir. [PDF]
Bovine digital dermatitis (DD) is the most important infectious disease associated with lameness in cattle worldwide. Since the disease was first described in 1974, a series of Treponema species concurrent with other microbes have been identified in DD ...
Martin Zinicola +7 more
doaj +5 more sources
Phenotypic and proteomic characterization of treponemes associated with bovine digital dermatitis [PDF]
Bovine digital dermatitis (BDD) is a multifactorial polymicrobial infectious disease associated with multiple species and phylotypes of treponemes. However, despite the abundance of molecular signatures for treponemes that are identified in bovine lesions, relatively few isolates are cultured, and even fewer have been characterized at the level of ...
Jarlath E Nally +2 more
exaly +7 more sources
Host Factors Impacting the Development and Transmission of Bovine Digital Dermatitis [PDF]
This review provides insight on potential host-specific factors that increase individual susceptibility to infection and transmission of bovine digital dermatitis. Digital dermatitis is increasing in prevalence within herds worldwide and yields economic losses for producers and welfare issues for animals.
Alicia T. Corlevic, David S. Beggs
core +6 more sources
Spirochaetes and other bacterial species associated with bovine digital dermatitis [PDF]
The 16S rRNA genes from spirochaetes associated with digital dermatitis of British cattle were amplified by polymerase chain reaction from digital dermatitis lesion biopsies using one universal and one treponeme-specific primer. Two treponemal sequences were identified both of which shared a high degree of homology with the oral pathogen Treponema ...
Collighan, RJ, Woodward, MJ
openaire +6 more sources
Genomic Detection of Bovine Digital Dermatitis Treponemes in Sole Ulcers [PDF]
Objective- Evaluation of possible contamination of sole ulcers with digital dermatitis Treponema spp . Design- Clinical detection Animals- Thirty-three cows with sole ulcer lesion.
Zahra Ghorbani +4 more
doaj +2 more sources
Experimental Transmission of Bovine Digital Dermatitis to Sheep: Development of an Infection Model [PDF]
Digital dermatitis is an infectious cause of lameness primarily affecting cattle but also described in sheep, goats, and wild elk. Digital dermatitis is a polymicrobial infection, involving several Treponema species and other anaerobic bacteria. Although the exact etiology has not been demonstrated, a number of bacterial, host, and environmental ...
Jennifer H, Wilson-Welder +5 more
openaire +4 more sources
First description of interdigital hyperplasia associated with contagious ovine digital dermatitis in two sheep [PDF]
Interdigital hyperplasia (IH) is a fold of fibrous tissue protruding into the interdigital space that rarely occurs in sheep. Interdigital hyperplasia secondary infected with bovine digital dermatitis (BDD) treponemes has been reported in cattle in the ...
Maher Alsaaod +6 more
doaj +3 more sources

